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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AGL
All Species:
13.03
Human Site:
S1290
Identified Species:
26.06
UniProt:
P35573
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P35573
NP_000019.2
1532
174764
S1290
A
V
E
I
V
G
L
S
K
S
A
V
R
W
L
Chimpanzee
Pan troglodytes
XP_524777
1532
174746
S1290
A
V
E
I
V
G
L
S
K
S
A
V
R
W
L
Rhesus Macaque
Macaca mulatta
XP_001106231
1532
174684
S1290
A
V
E
I
V
G
L
S
K
S
A
V
R
W
L
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
NP_001074795
1532
174269
C1290
A
V
E
I
V
G
L
C
K
S
A
V
R
W
L
Rat
Rattus norvegicus
NP_001102034
1532
174314
C1290
A
V
E
I
V
G
L
C
K
S
A
V
R
W
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512323
1163
131293
K933
R
W
L
V
E
L
S
K
K
N
V
F
P
Y
H
Chicken
Gallus gallus
XP_422317
1532
174660
C1290
A
V
E
I
V
G
L
C
K
S
A
V
R
W
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_696194
1052
117860
K822
R
W
L
V
E
L
H
K
K
G
L
F
P
Y
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_726062
1629
183200
Q1386
A
V
E
L
V
G
L
Q
Y
A
V
L
R
F
M
Honey Bee
Apis mellifera
XP_394961
1549
176545
S1290
A
V
E
I
V
G
L
S
K
S
I
L
S
F
L
Nematode Worm
Caenorhab. elegans
NP_496984
1467
165910
Q1231
D
G
A
A
V
E
L
Q
G
L
A
Y
R
A
L
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q06625
1536
174953
L1278
A
I
E
I
N
G
L
L
K
S
A
L
R
F
V
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
97.6
N.A.
N.A.
91.9
92.1
N.A.
67.6
81.7
N.A.
53.3
N.A.
45.2
49.9
44.2
N.A.
Protein Similarity:
100
100
99.2
N.A.
N.A.
96.6
96.4
N.A.
72
91.5
N.A.
61.3
N.A.
61.4
66.6
62
N.A.
P-Site Identity:
100
100
100
N.A.
N.A.
93.3
93.3
N.A.
6.6
93.3
N.A.
6.6
N.A.
46.6
73.3
33.3
N.A.
P-Site Similarity:
100
100
100
N.A.
N.A.
93.3
93.3
N.A.
26.6
93.3
N.A.
20
N.A.
80
86.6
33.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
35.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
52.9
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
60
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
86.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
75
0
9
9
0
0
0
0
0
9
67
0
0
9
0
% A
% Cys:
0
0
0
0
0
0
0
25
0
0
0
0
0
0
0
% C
% Asp:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
75
0
17
9
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
17
0
25
0
% F
% Gly:
0
9
0
0
0
75
0
0
9
9
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
9
% H
% Ile:
0
9
0
67
0
0
0
0
0
0
9
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
17
84
0
0
0
0
0
0
% K
% Leu:
0
0
17
9
0
17
84
9
0
9
9
25
0
0
67
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% M
% Asn:
0
0
0
0
9
0
0
0
0
9
0
0
0
0
9
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
17
0
0
% P
% Gln:
0
0
0
0
0
0
0
17
0
0
0
0
0
0
0
% Q
% Arg:
17
0
0
0
0
0
0
0
0
0
0
0
75
0
0
% R
% Ser:
0
0
0
0
0
0
9
34
0
67
0
0
9
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
67
0
17
75
0
0
0
0
0
17
50
0
0
9
% V
% Trp:
0
17
0
0
0
0
0
0
0
0
0
0
0
50
0
% W
% Tyr:
0
0
0
0
0
0
0
0
9
0
0
9
0
17
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _